2. Jakobson, C.†, Hartl, J.†, Trebulle, P., Mulleder, M., Jarosz, D.#, and Ralser, M.#. “A genome-to-proteome atlas charts natural variants controlling proteome diversity and forecasts their fitness effects.” bioRxiv: https://www.biorxiv.org/content/10.1101/2024.10.18.619054v1
1. Jakobson, C.†, Aguilar-Rodríguez, J.†, and Jarosz, D. “Hsp90 shapes adaptation by controlling the fitness consequences of regulatory variation.” bioRxiv: https://www.biorxiv.org/content/10.1101/2023.10.30.564848v1
18. Aguilar-Rodríguez, J.†, Jakobson, C.†, and Jarosz, D. (2024) “The Hsp90 molecular chaperone as a global modifier of the genotype-phenotype-fitness map: An evolutionary perspective.” Journal of Molecular Biology. DOI: 10.1016/j.jmb.2024.168846. [Review]
17. Garcia, D.†, Campbell, E.†, Jakobson, C., Tsuchiya, M., Shaw, E., DiNardo, A., Kaeberlein, M., and Jarosz, D. (2021) “A prion accelerates proliferation at the expense of lifespan.” eLife. DOI: 10.7554/eLife.60917.
16. Jakobson, C. and Jarosz, D. (2020) “What Has a Century of Quantitative Genetics Taught Us About Nature’s Genetic Toolkit?” Annual Review of Genetics. DOI: 10.1146/annurev-genet-021920-102037. [Review]
15. Itakura, A.†, Chakravarty, A.†, Jakobson, C., and Jarosz, D. (2019) “Widespread Prion-Based Control of Growth and Differentiation Strategies in Saccharomyces cerevisiae.” Molecular Cell. DOI: 10.1016/j.molcel.2019.10.027.
14. Jakobson, C. and Jarosz, D. (2019) “Molecular origins of complex heritability in natural genotype-to- phenotype relationships.” Cell Systems. DOI: 10.1016/j.cels.2019.04.002. Cell Systems Featured Article May 2019
13. Jakobson, C., She, R., and Jarosz, D. (2019) “Pervasive function and evidence for selection across standing genetic variation in S. cerevisiae.” Nature Communications. DOI: 10.1038/s41467-019-09166-1.
12. Jakobson, C., Tullman-Ercek, D., and Mangan, N. (2018) “Spatially organizing biochemistry: choosing a strategy to translate synthetic biology to the factory.” Scientific Reports. DOI: 10.1038/s41598-018-26399- 0.
11. Hartman, E., Jakobson, C., Favor, A., Lobba, M., Álvarez-Benedicto, E., Francis, M., and Tullman-Ercek, D. (2018) “Quantitative characterization of all single amino acid variants of a viral capsid-based drug delivery vehicle.” Nature Communications. DOI: 10.1038/s41467-018-03783-y. Editors’ Highlights selection for Therapeutics
10. Jakobson, C. and Jarosz, D. (2017) “Organizing biochemistry in space and time using prion-like self-assembly.” Curr. Opin. In Systems Biology. DOI: 10.1016/j.coisb.2017.11.012. [Review]
9. Jakobson, C., Slininger Lee, M., Tullman-Ercek, D., and Mangan, N. (2017) “A systems-level model reveals that 1, 2-Propanediol utilization microcompartments enhance pathway flux through intermediate sequestration.” PLoS Comp. Biol. DOI: 10.1371/journal.pcbi.1005525.
8. Slininger Lee, M., Jakobson, C., and Tullman-Ercek, D. (2017) “Evidence for Improved Encapsulated Pathway Behavior in a Bacterial Microcompartment through Shell Protein Engineering.” ACS Synthetic Biology. DOI: 10.1021/acssynbio.7b00042.
7. Jakobson, C., Slininger Lee, M., and Tullman-Ercek, D. (2017) “De Novo Design of Signal Sequences to Localize Cargo to the 1,2-Propanediol Utilization Microcompartment.” Protein Science. DOI: 10.1002/pro.3144.
6. Asensio, M.†, Morella, N.†, Jakobson, C., Hartman, E., Glasgow, J., Sankaran, B., Zwart, P., and Tullman- Ercek, D. (2016) “A single amino acid change alters the stable structure of a virus-like particle.” Nano Letters. DOI: 10.1021/acs.nanolett.6b02948.
5. Jakobson, C., Chen, Y., Slininger, M., Valdivia, E., Kim, E., and Tullman-Ercek, D. (2016) “Tuning the Catalytic Activity of Subcellular Nanoreactors.” Journal of Molecular Biology. DOI: 10.1016/j.jmb.2016.07.006.
4. Jakobson, C. and Tullman-Ercek, D. (2016) “Dumpster diving in the gut: microcompartments as part of a host-associated lifestyle.” PLoS Pathogens. DOI: 10.1371/journal.ppat.1005558. [Review]
3. Jakobson, C., Kim, E., Slininger, M., Chien, A., and Tullman-Ercek, D. (2015) “Localization of Proteins to the 1,2-Propanediol Utilization Microcompartment by Non-native Signal Sequences Is Mediated by a Common Hydrophobic Motif.” The Journal of Biological Chemistry. DOI: 10.1074/jbc.M115.651919.
2. Glasgow, J., Asensio, M., Jakobson, C., Francis, M., and Tullman-Ercek, D. (2015) “The Influence of Electrostatics on Small Molecule Flux through a Protein Nanoreactor.” ACS Synthetic Biology. DOI: 10.1021/acssynbio.5b00037.
1. Kim, E.†, Jakobson, C.†, and Tullman-Ercek, D. (2014) Engineering transcriptional regulation to control Pdu microcompartment formation. PLoS ONE. DOI: 10.1371/journal.pone.0113814.
2023 Stanford University Developmental Biology Department Retreat, Monterey, CA
2023 Molecular Mechanisms in Evolution Gordon Research Seminar & Conference, Easton, MA
2022 Stanford University Chemical and Systems Biology Department Retreat, Asilomar, CA
2022 Discussing Developmental Data (3D) Seminar, Stanford, CA
2021 Stanford University Microbial Data and Journal Club (Bug Club), Stanford, CA
2021 Stanford University Chemical and Systems Biology Department Retreat, Santa Cruz, CA
2021 Stanford University Developmental Biology Department Retreat, Stanford, CA
2020 Discussing Developmental Data (3D) Seminar, Stanford, CA
2019 American Institute of Chemical Engineers Annual Meeting, Orlando, FL
2019 Systems Biology: From Genomes to Complex Traits, EMBL, Heidelberg, Germany
2019 Stanford University Developmental Biology Department Retreat, Monterey, CA
2019 Stanford University Intrinsically Disordered Protein Scientific Interest Group (IDPSIG), Stanford, CA
2019 Synthetic Biology Gordon Research Seminar & Conference, Waterville Valley, NH
2019 American Chemical Society Spring Meeting, Orlando, FL
2018 American Institute of Chemical Engineering Annual Meeting, Pittsburgh, PA
2018 Experimental Approaches to Evolution and Ecology, EMBL, Heidelberg, Germany
2018 Computational, Evolutionary, and Human Genetics (Evolgenome) Seminar, Stanford, CA
2018 Stanford University Chemical and Systems Biology Department Retreat, Santa Rosa, CA
2018 American Chemical Society Spring Meeting, New Orleans, LA
2017 Stanford University Microbial Data and Journal Club (Bug Club), Stanford, CA
2017 Stanford ChEM-H Postdoc Retreat, Rohnert Park, CA
2016 American Institute of Chemical Engineers Annual Meeting, San Francisco, CA
2016 Engineering Biology Research Consortium (EBRC) Fall Retreat, Pasadena, CA
2016 Amyris Inc., Emeryville, CA
2016 Department of Chemical and Biomolecular Engineering Colloquium, Berkeley, CA
2016 Synthetic Biology Engineering Research Center (SynBERC) Spring Retreat, Berkeley, CA
2016 American Chemical Society Spring Meeting, San Diego, CA
2015 American Institute of Chemical Engineering Annual Meeting, Salt Lake City, UT
2015 Microbiology Student Group Student Symposium, Berkeley, CA
2014 Microbiology Student Group Student Symposium, Berkeley, CA